Histological examination: price, methods of taking material, the result

August 12, 2017 23:00 | Methods Of Diagnosis

Histological examination is a diagnostic technique in which tissues are examined by microscopic examination.They are taken for analysis by biopsy from a pathological or healthy area, and sometimes internal organs are used.This type of diagnostics plays the greatest role in a variety of tumors.And today we will tell you whether errors are possible in the study of histological material, what are its main methods, and also about how the procedure is going on.

What histological examination

To diagnose enough to take a small sample to determine the exact disease that provoked the pathological process, its character, stage, and other important details.The study itself includes a biopsy and a direct examination of the seized material.

This method of diagnosis is used in cases where other types of examinations do not work even in a complex. Often confined to a single brushstroke, but in general the list of diseases has to be fully implemented.

That is the histological study, tells this video:

To appoint his

valuable to research in various fields of medicine.So, use it for the selection of a suitable treatment program for diseases of the following sections:

  • urology,
  • otorhinolaryngology,
  • gastroenterology,
  • nephrology,
  • endocrinology,
  • pulmonology,
  • hematology,
  • gynecology.

It is necessary in thoracic and abdominal surgery.

Why produce such a study

Gistologicheskoe-issledovanie-2 Appointed histological examination only in a specific list of cases.Basically it is needed to clarify the diagnosis, but there are other situations where it is necessary to conduct:

  1. Differential diagnosis.
  2. Determining the need for an operation.
  3. Study of the dynamic growth of neoplasm.
  4. Monitoring the effectiveness of treatment, identifying changes in the picture of the disease.
  5. Determination of the extent of tumor growth.
  6. Help in detecting cancer at an early stage.

A study of chemotherapy and radiation therapy precedes.The process of cancer treatment is not without him, as the procedure helps to control the course of recovery.

Next we will tell you about the types of histological studies and modern methods of taking material for them.


procedure In order to obtain material for study, it must be separated from the internal tissues or organs.A biopsy with histological examination is exposed to the skin, bronchial mucosa or intestines, lymph nodes, muscles.The take is made by several types of biopsy:

  1. Spiked .By means of the tool the necessary quantity of a fabric is bored.
  2. Excision .The material is taken at the time of surgery.
  3. Puncture .Use different designs of needles, which pierce neoplasms and gain pathological infiltrate.
  4. Intrusion .Part of the affected organ or tissue is excised for examination.
  5. Curettage of cavities of .Used as a standard method for osteomyelitis or cervix, other cavities( including those formed by the pathological process).
  6. Trepan biopsy .Used to extract liquids from the bone.

Material can be taken by flushing or brushing, as well as by open method.For accuracy at the time of the biopsy, ultrasound or X-ray, MRI, is used.

About the methods of histological research will tell this video:

Indications for the

  • pathological processes in the lungs, retroperitoneal space, in the digestive tract;
  • of the thyroid cyst;
  • abscess;
  • dermatitis( including purpurea, follicular, dying, infectious, bullous)
  • lymphadenopathy;
  • skin erosion;
  • cystic acne;
  • carcinoma;
  • Norwegian type of scabies;
  • tumor of the kidney or parenchyma;
  • pericardial effusion, ascites;
  • vitiligo;
  • for children's eczema;
  • primary focal lesions;
  • hydradenitis of the scalp;
  • pathological diffuse or focal processes;
  • neoplasm.

The decision on the need for histological examination in other diseases will be decided by the doctor.However, the patient himself can refuse it.

Contraindications for carrying out


  • hypocoagulation;
  • unconscious state;
  • intolerance to anesthetics;
  • menstruation;
  • lack of consent;
  • thrombocytopenia;
  • bleeding disorder;
  • melanoma;
  • threat of termination of pregnancy.

To the relative list of contraindications include:

  • ascites,
  • hyperbilirubinemia,
  • pleurisy,
  • cirrhosis,
  • heart failure.

Is the procedure

safe? Biopsy under the control of an MRI or X-ray is completely safe.

On preparation for tests and histological methods of research, read below.

Preparation for

Liquid and food should be discontinued 8 hours before the biopsy. At the preparation stage it is important to consult a doctor to get the appropriate recommendations.You may need to stop taking certain medications or adjust their dosage.To inform the doctor about all medications, as well as about the diseases, the presence of allergy, the transferred interventions.

Women should additionally be informed of pregnancy, since some types of biopsy for histological examination are prohibited during this period.There is no specific training.

On the conduct of histological studies, read on.

How the procedure passes

The biopsy of the material precedes the diagnosis.Further, the material is immediately delivered for histological examination, but it is permissible to place it in a solution of formalin and alcohol if this process is postponed. The amount of liquid directly depends on the size of the tissue taken.The number should be 30 times larger.

Histological examination can be preceded by a cytological test.It is preliminary, but more rapid.

The procedure for taking and correctness of its conduct plays a huge role.So, an incorrect intake of fluid leads to a mistaken diagnosis.

The interpretation of the results of the histological examination of the biopsy material is discussed below.

Explanation of results

Gistologicheskoe-issledovanie-3 The material is provided to the pathologist or pathologist for analysis.The histological examination can be divided into macroscopic and microscopic diagnostics.In the first case, the color of the tissue is determined, its size, what is it different from the norm, are there any deviations( germination, substitution, softening, etc.).A more detailed diagnosis is carried out by means of microscopy.

The decoding takes into account other clinical data, the overall picture of the disease, and the analysis.All this is usually enough to make an accurate diagnosis, but sometimes all the data is not enough to determine only one disease.In this case, the doctor notes the peculiarities of the pathological changes that affected the tissue, which will help in differential diagnosis.If the case is controversial, conduct medical consultations. The decryption time is 1-2 weeks.

The price for the histological examination of the biopsy material is indicated below.

Average cost of procedure

The price of a histological examination depends directly on the complexity.So, if you need a biopsy, the cost can be 4 thousand rubles.

If procedure of complexity does not represent, then it will be necessary to pay for diagnostics 1500-2000 rubles.This is the cost of a histological examination of the biopsy specimen.

The difference between cytological and histological research will be told by this video: