Fluoxetine as a drug: effects on the body, effects, overdose, doctors' reviews

August 12, 2017 15:31 | Addiction

One of the most popular antidepressants in the world is Fluoxetine, which is Prozac.Like its analogs, this drug is addictive, as a result of which patients are "attached" to it as a drug.What is a common antidepressant and what exactly is it dangerous?

Antidepressant Fluoxetine as a drug

Prozac, more commonly known under the trademark Fluoxetine, is a drug from the group of antidepressants.It is prescribed in the treatment of depression and obsessive conditions, in which the patient experiences constant fear and increased anxiety.

The drug has been actively used in the treatment of depressive disorder since 1980, when in America the prevalence of this disease has already taken the scale of a national catastrophe.Residents of the USA and Canada began to be actively treated with a new drug, as a result of which they began to call themselves "the generation of Prozac".Now, according to statistics, Fluoxetine is taken by 40 million people around the world.

So, some girls use the drug for weight loss, b

ecause Prozac reduces appetite.The danger is that it has the property of accumulating in the body, as a result of which serious lesions of the central nervous system develop.

Although the antidepressant is intended to restore traction to life, with prolonged use the effect becomes reversed.Initially, a side effect in the form of euphoria is possible.However, later the person begins to be haunted by nightmares, he develops neuroses and suicidal tendencies.


The preparation Fluoxetine is mainly prescribed for mental disorders, among which:

  • Depression.
  • Compulsive disorder.
  • Bulimia.

According to some information, the drug also helps with anorexia nervosa, alcoholism, social phobia, diabetic neuropathy, affective disorders, autism, panic attacks, kleptomania.A complete list of additional indications for use is very broad, but at the same time it is controversial.There are research data, according to which the effect of using Prozac is comparable to the action of "placebo."

Photo of tablets Fluoxetine

Indications and side effects of fluoxetine

Principle of operation

Fluoxetine selectively inhibits the reuptake of serotonin in brain cells.As a result, the concentration of this substance increases in the synapses responsible for the transfer of neurotransmitters from the neuron to the neuron.The effect of serotonin on the postsynaptic links of the receptors is prolonged, while the drug does not affect the reuptake of dopamine, norepinephrine and other neurotransmitters.

This is the pharmacological action of fluoxetine.Externally, it manifests itself in improving mood and stimulating effect.At the same time, anxiety disappears, appetite decreases, but the drug does not have a calming effect.

It is possible to trace the relationship between the action on the organism of Prozac and the drug.This antidepressant has a very strong effect and seriously affects the nervous system.

Uncontrolled taking of tablets instead of returning to cravings provokes the re-development of obsessive-compulsive disorders.After a brief euphoria, a person has obsessive thoughts that do not give him peace and force him to take action to overcome them.

There are also cases of hallucinations and psychoses in the background of the use of Prozac.All this often leads to attempts at suicide, the risk of which is especially high at the age of 24 years.
On the video about the effect of antidepressants on the body:

Danger and side effects

Long-term use of fluoxetine, especially when self-administered, is fraught with many side effects from virtually all organs and systems.About this in Canada, where the medicine has become incredibly popular, even filmed a film called "Generation Prozac."It was shown in Russia, but the video did not provoke public resonance.

The main danger of an antidepressant is its action on the central nervous system, from which it is possible:

Dizziness and headaches;
  • ;
  • nightmares;
  • euphoria;
  • anxiety;
  • psychomotor agitation;
  • neuroses;
  • thinking disorder;
  • loss of coordination of movements;
  • attention violations;
  • lethargy.

In the 1980s, during the testing in Germany, the licensing authority of the country established: Fluoxetine is absolutely not suitable for the treatment of depression.Then the scientists found out that the drug causes hallucinations and psychoses, but in general, its side effects reach an unacceptable level of medicine.

In addition, according to unofficial statistics, Fluoxetine provokes 5.6 times more suicide attempts than other antidepressants.Only among Americans over the course of 9 years 4 million people have experienced a fatal reaction to the drug.

Also widely accepted worldwide fame was shooting at the American school in 2005. The young man who took Prozak was a criminal.Subsequently, this drug scored the highest ever record of complaints related to the huge number of side effects, suicides and crimes committed under its influence.

In addition to the CNS, fluoxetine affects the cardiovascular system and blood, provoking:

  • cardiac rhythm disturbances;
  • Vascular thrombosis;
  • cardiac arrest;
  • vasculitis;
  • heart failure;
  • myocardial infarction;
  • anemia;
  • leukocytosis;
  • cerebral ischemia.

Serious defeat of the antidepressant can cause damage to the organs of the gastrointestinal tract, which provokes:

  • decreased appetite;
  • anorexia;
  • increased salivary glands;
  • peptic ulcer;
  • constipation and diarrhea;
  • intestinal obstruction;
  • colitis;
  • gastritis;
  • intestinal obstruction;
  • pancreatitis.

Reduced appetite often leads to anorexia, which is why some girls take the drug in order to lose weight.Also described are cases where fluoxetine led to an increase in tonsils, pharyngitis, chills and fever, malignant neuroleptic syndrome and even death.


Overdose with Fluoxetine As a result of an overdose of the drug, all side effects are exacerbated.

The first symptoms to look out for are:

  • Nausea with vomiting.
  • Anxiety.
  • The excited state.
  • Convulsions.
  • Epileptic seizures.

Also officially recorded 2 deaths due to an overdose of Fluoxetine.The patients took the drug simultaneously with Codeine, Temazepam and Maprotilin.

Prozac's antidote does not exist as such.Therefore, at the first signs of an overdose, a person should urgently conduct a lavage of the stomach and give him a drink of activated charcoal.

Subsequently, the patient will require symptomatic and supportive treatment.As medical practice shows, hemodialysis, diuretics and blood transfusion with an overdose of Fluoxetine are futile.


Due to the large number of suicides influenced by Prozac, this drug caused a lot of scandals in Europe.As a result, in some countries it was officially banned and withdrawn from sale.In Russia, despite all the worries around the antidepressant, he was included in the Register of Medicines and allowed for free sale in pharmacies.

Buy fluoxetine only by prescription.However, the wide popularity of the drug throughout the world leads to the fact that some people acquire it illegally.On the Internet, even companies that offer related services operate.

Reviews of Physicians

Although fluoxetine causes many side effects, doctors continue to prescribe it to their patients.However, most of them note that this drug shows a positive result only in severe forms of depression.In all other cases, the antidepressant acts as a placebo.

There is also an opposite opinion on the effect of fluoxetine.Thus, scientists from the University of Hull announced the results of a number of studies of the drug.

According to the data obtained, even with severe depression, this drug acts just like a dummy without an active substance.Positive dynamics was observed only in a small part of the subjects.Accordingly, American scientists argue that the appointment of fluoxetine is inappropriate in most cases.

All physicians converge in only one.Fluoxetine is a potent drug, so self-medication is unacceptable.Antidepressant should be used only on the recommendation of the attending physician and under his supervision.